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and diphenylene iodonium, an inhibitor of NOX, in attenuating ROS-induced apoptosis

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They are used in pharmaceutical research, biotechnology, formulation studies, and laboratory development

It combines linagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, which enhances incretin effects to increase insulin secretion and decrease glucagon release in a glucose-dependent manner, with metformin extended-release (E R.), a biguanide that reduces hepatic glucose production and improves insulin sensitivity